It may take several days to a few weeks after exposure to develop symptoms. Early symptoms of monkeypox include flu-like symptoms such as: Fever. Chills. Headache. Muscle pain. Fatigue. Lymph nodes that are swollen. A rash usually appears within a few days. The rash begins with flat, red pimples that can be unpleasant. These lumps develop into blisters that fill with pus. The blisters eventually harden over and fall off; the entire process can take two to four weeks. Sores in the mouth, vagina, or anus are also possible. Not everyone who has monkeypox experiences all of the symptoms. In reality, many cases in the current (2022) outbreak are not following the typical pattern of symptoms. This unusual presentation comprises only a fe