The collection of symptoms that strike women in the week or so before their menstrual cycle begins, has been the brunt of countless jokes and has even been suggested as a reason why a woman should not be elected president of the United States. Men, on the other hand, should stop giggling because medicine recognizes the male equivalent known as "irritable male syndrome," a behavioral state defined as "hypersensitivity, frustration, anxiety, and anger that occurs in males and is associated with biochemical changes, hormonal fluctuations, stress, and loss of male identity."